Nonoxynol-5

AKA: 4-Methoxypicolinamide, 90151-10-3, 4-methoxypyridine-2-carboxamide, 4-Methoxy-pyridine-2-carboxylic acid amide, 9014-93-1, 4-Methoxypyridine-2-carboxylic acid amide, 2-Pyridinecarboxamide
Synthetic
Cleanser
Emulsifier
Not Clean
OriginDerived from nonylphenol, a synthetic organic compound created through the alkylation of phenol with nonene. Produced through ethoxylation, where ethylene oxide is added to nonylphenol to create the polyethylene glycol ether surfactant.
Poly(oxy-1,2-ethanediyl), .alpha.-(dinonylphenyl)-.omega.-hydroxy- (5 mol EO average molar ratio)
Formula
C7H8N2O2
Mol. Weight
152.15
CAS #
9014-93-1
Form
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Functions
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Emulsifier
Mixes Oil & Water
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory0 listings
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Eye Irritant in Testing
1 study / 1 irritating / reactions severe (CIR 44)
Skin Irritant in Testing
2 studies / 2 irritating / reactions mild to severe (CIR 44 and 695)
Concentration Guide
CIR's newest survey reports no concentration of use.
CIR · 2014 survey
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR
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