Nonoxynol-8

AKA: 41506-14-3, Octaethylene glycol mono(p-nonylphenyl) ether, Nonylbenzene-PEG8-OH, 23-(4-Nonylphenoxy)-3, 6, 9, 12, 15, 18, 21-heptaoxatricosan-1-ol, Rokafenol N-8, 27177-05-5, 23-(Nonylphenoxy)-3
Synthetic
Cleanser
Not Clean
Poly(oxy-1,2-ethanediyl), .alpha.-(dinonylphenyl)-.omega.-hydroxy-, phosphate, (8 mol EO average molar ratio)
Formula
C31H56O9
Mol. Weight
572.80
CAS #
39464-64-7
Form
Liquid
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Removes Impurities
Cleansing Surfactant
Traditional Use
Synthetic nonionic surfactant developed in the mid-20th century. Used in cosmetics and personal care as an emulsifier and solubilizer.
EWG
4
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
medical-approval
all-shades-safe
Moderate Irritant
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory0 listings
🛡️Safety-assessed2 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR