Oleamidopropyl Betaine

Oleamidopropyl Betaine 1
molecular structure · PubChem CID 6436555
AKA: Oleamidopropyl dimethyl glycine, (Z)-(Carboxymethyl)dimethyl-3-[(1-oxo-9-octadecenyl)amino]propylammonium hydroxide, (Z)-(Carboxymethyl)dimethyl-3-((1-oxo-9-octadecenyl)amino)propylammonium hydroxide, 1-Propanaminium, N-(carboxymethyl)-N, Hydroxide, Inner salt
Synthetic
Cleanser
Skin Conditioner
Hair Care
Not Clean
OriginDerived from oleic acid and dimethylaminopropylamine, both petroleum-based or fatty acid-derived compounds. Synthesized through condensation reaction between oleic acid derivatives and betaine-type compounds.
(Z)-(Carboxymethyl)dimethyl-3-[(1-oxo-9-octadecenyl)amino]propylammonium hydroxide
Formula
C25H48N2O3
Mol. Weight
424.70
CAS #
25054-76-6
Form
Liquid
State
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Antistatic
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Foam Boosting
Locks in moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
5
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Skin Irritant in Testing (CIR report on the ingredient group)
CIR report statement covering this group of ingredients / not tested individually (CIR 518)
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR