Oleic Acid

AKA: 112-80-1, Cis-9-Octadecenoic acid, (Z)-Octadec-9-enoic acid, Cis-Oleic acid, Wecoline OO, Elaidoic acid, Vopcolene 27, Glycon wo, Glycon RO
Plant-Derived Synthetic
Emollient
Cleanser
Emulsifier
Skin Conditioner
Acid
Clean
OriginNative to Global (Found in various plant & animal fats). Derived from plant oils including olives, avocados, and various nuts through natural fat sources. Extracted via cold-pressing or obtained through saponification and separation from plant triglycerides.
Oleic acid is an unsaturated fatty acid that occurs naturally in various animal and vegetable fats and oils. It is an odorless, colourless oil, although commercial samples may be yellowish. In chemical terms, oleic acid is classified as a monounsaturated omega-9 fatty acid. It has the formula CH3(CH2)7CH=CH(CH2)7COOH. The term "oleic" means related to, or derived from, oil or olive, the oil that is predominantly composed of oleic acid. Oleic acid is the most widely distributed and abundant fatty acid in nature. It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent. Oleic acid is a major constituent of plant oils e.g. olive oil (about 80%), almond oil (about 80%) and many others, mainly as glyceride. It is also a constituent of tall oil and present in fruits. Oleic acid is a food additive and is used in manufacturing of surfactants, soaps, plasticizers. It is also an emulsifying agent in foods and pharmaceuticals. Oleic acid is a known skin
Solubility Insoluble (NTP, 1992)
Formula
C18H34O2
Mol. Weight
282.50
CAS #
112-80-1
Form
Liquid
Skin Types
●all-skin-types, gentle
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Locks In Moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not Phototoxic
Product formulation test found no phototoxicity in the CIR safety assessment (CIR 161 and 777)
Mixed Sensitization Results
10 studies / 2 sensitizing / 1 mixed / 7 not sensitizing (CIR 161 and 777)
Comedogenic in Testing
Animal test with a comedogenic result in the CIR safety assessment (CIR 161 and 777)
Mixed Eye Irritation Results
7 studies / 3 mixed / 4 not irritating / reactions minimal to slight (CIR 161 and 777)
Mixed Skin Irritation Results
19 studies / 10 irritating / 5 mixed / 4 not irritating / reactions minimal to moderate (CIR 161 and 777)
Concentration Guide
Leave-on0.0002–17%
Rinse-off0.0005–20.9%
0%50%100%
CIR reported use · 2016 survey
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR
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