Oleoyl Sarcosine

AKA: N-Oleoylsarcosine, Oleyl sarcosine, 110-25-8, Oleoylsarcosine, Sarkosyl O, N-Methyl-N-oleoylglycine, Oleic sarcosine, Hamposyl O, Maprosyl O
Synthetic
Cleanser
Skin Conditioner
Hair Care
Clean
OriginDerived from oleic acid and sarcosine, both synthetic or derived from natural oils and amino acids. Synthesized through amide bond formation between oleic acid and sarcosine via chemical condensation.
(Z)-N-Methyl-N-(1-oxo-9-octadecenyl)glycine
Formula
C21H39NO3
Mol. Weight
353.50
CAS #
110-25-8
Form
Liquid
State
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Antistatic
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Reduces Static
Removes Impurities
Conditions Hair
Cleansing Surfactant
Locks In Moisture
Removes dirt and impurities
Lifts away dirt and oil
Reduces flyaways
Softens and detangles hair
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
1 study / 1 not sensitizing (CIR 719)
Phototoxic in Testing
Animal test with a phototoxic or photosensitizing result in the CIR safety assessment (CIR 719)
Skin Irritant in Testing
1 study / 1 irritating (CIR 719)
Eye Irritant in Testing
2 studies / 2 irritating / reactions moderate (CIR 719)
Concentration Guide
CIR's newest survey reports no concentration of use.
CIR · 2015 survey
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR
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