murphyOxyquinoline
AKA: 8-HYDROXYQUINOLINE, Quinolin-8-ol, 148-24-3, 8-quinolinol, Oxine, Quinophenol, Oxychinolin, Phenopyridine, 8-Quinol
Synthetic
Preservative
Chelating Agent
Not Clean
OriginOxyquinoline is synthesized from quinoline, a nitrogen-containing aromatic compound derived from coal tar or petroleum sources. It is produced through oxidation reactions that introduce oxygen functional groups into the quinoline ring structure.
8-Hydroxyquinoline; 1-Azanaphthalene-8-ol; Quinolin-8-ol; 8-Quinolinol; Phenopyridine
Solubility less than 1 mg/mL at 61 °F (NTP, 1992)
Formula
C9H7NO
Mol. Weight
145.16
CAS #
148-24-3
Form
Powder
State
8-hydroxyquinoline appears as white to off-white or faintly yellow crystalline powder. Phenolic odor. (NTP, 1992)
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
No
Functions
Antimicrobial
Keeps your product from growing bacteria, mold, or yeast. Without these, that jar of cream becomes a petri dish in about a week.
Chelating
Grabs onto metal ions in water that would destabilize the formula. Keeps your product from going bad or changing color.
Fights Bacteria
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
6
CIR
Safe as used · CIR insufficient data requested (2026)
Pregnancy
No
CIR Safety Findings
Not a Sensitizer
1 study / 1 not sensitizing (CIR 387)
Mixed Skin Irritation Results
5 studies / 4 irritating / 1 not irritating / reactions mild to moderate (CIR 105 and 387)
Eye Irritant in Testing
2 studies / 2 irritating / reactions slight (CIR 105)
Concentration Guide
0%50%100%
Reg. limit 0.3%
EU regulatory limit: 0.3%. (a) 0.3% (as base) (b) 0.03% (as base) Source: EU Cosmetics Regulation (EC) 1223/2009, Annex III (Restricted Substances), Entry 51.
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR