murphyOxyquinoline Sulfate
AKA: 8-Hydroxyquinoline sulfate, Hydroxyquinoline sulfate, Oxine sulfate, Oxyquinoline sulphate, 8-Quinolinol sulfate (2:1) (salt), CRIPTONOL
Synthetic
Preservative
Chelating Agent
Not Clean
OriginOxyquinoline sulfate is synthesized from quinoline, a nitrogen-containing aromatic compound derived from coal tar or petroleum sources. The compound is produced through sulfonation of oxyquinoline, where sulfuric acid adds sulfate groups to the oxyquinoline molecule.
bis(8-Hydroxyquinolinium) sulphate
Solubility greater than or equal to 100 mg/mL at 66 °F (NTP, 1992)
Formula
C18H16N2O6S
Mol. Weight
388.40
CAS #
134-31-6
Form
Powder
State
8-hydroxyquinoline sulfate is a pale yellow to yellow crystalline powder with a slight saffron odor. Burning taste. (NTP, 1992)
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
No
Functions
Antimicrobial
Keeps your product from growing bacteria, mold, or yeast. Without these, that jar of cream becomes a petri dish in about a week.
Chelating
Grabs onto metal ions in water that would destabilize the formula. Keeps your product from going bad or changing color.
Fights Bacteria
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
6
CIR
Insufficient data
Pregnancy
No
CIR Safety Findings
Not a Sensitizer (CIR report on the ingredient group)
CIR report statement covering this group of ingredients / not tested individually (CIR 387)
Not a Skin Irritant (CIR report on the ingredient group)
CIR report statement covering this group of ingredients / not tested individually (CIR 387)
Concentration Guide
0%50%100%
Reg. limit 0.3%
EU regulatory limit: 0.3%. (a) 0.3% (as base) (b) 0.03% (as base) Source: EU Cosmetics Regulation (EC) 1223/2009, Annex III (Restricted Substances), Entry 51.
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR