Palmitamidopropyl Betaine

AKA: Pendecamaine, Pendecamaina, Pendecamainum, Pendecamaine [INN:BAN], Pendecamainum [INN-Latin], Pendecamaina [INN-Spanish], 3-Palmitoylamidopropyl betaine
Synthetic
Cleanser
Skin Conditioner
Hair Care
Plant Oil
Not Clean
1-Propanaminium, N-(carboxymethyl)-N,N-dimethyl-3-[(1-oxohexadecyl)amino]-, inner salt
Formula
C23H46N2O3
Mol. Weight
398.60
CAS #
32954-43-1
Form
Liquid
State
Liquid
Functions
Antistatic
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Foam Boosting
Locks in moisture
Traditional Use
A synthetic amphoteric surfactant derived from palmitic acid and betaine, developed in the late 20th century as a mild, conditioning cleansing agent suitable for delicate skin and baby formulations.
EWG
3
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing
🛡️Safety-assessed0 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR