Palmitoyl Alanine

AKA: 56255-31-3, Palmitoyl-L-alanine, N-Hexadecanoyl-L-alanine, N-Palmitoyl-L-alanine, Codeage PA, Palmityl-L-alanine, L-Alanine
Synthetic
Barrier Support
Amino Acid
Not Clean
The panel concluded that the 115 amino acid alkyl amides listed below are safe in the present practices of use and concentration in cosmetics, when formulated to be non-irritating...Palmitoyl Alanine...
Formula
C19H37NO3
Mol. Weight
327.50
CAS #
56255-31-3
Form
Powder
Functions
Skin Protecting
Helps rebuild and strengthen your skin barrier — the invisible shield that keeps moisture in and irritants out. Essential after over-exfoliating or harsh weather.
Nourishes & Protects
Traditional Use
A synthetic peptide-lipid conjugate created by combining palmitic acid with the amino acid alanine, developed in recent decades as a skin-conditioning and bioactive ingredient with potential anti-inflammatory properties.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper
⚖️Regulatory1 listing
🛡️Safety-assessed1 review
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR