Palmitoyl Ethyltrimonium Methosulfate

AKA: Surfactive V 16, 116246-03-8, Palmitoyl ethyltrimonium methosulfate [INCI], Ethanaminium, Methyl sulfate, Methyl sulfate (1:1)
Synthetic
Cleanser
Emulsifier
Not Clean
OriginDerived from fatty acids and quaternary ammonium compounds, typically sourced from palm or coconut oil derivatives. Synthesized through quaternization of dimethylamino compounds followed by esterification with palmitic acid.
The CIR Expert Panel concluded the following ingredients are safe in the present practices of use and concentration described in the safety assessment when formulated to be non-irritating...Palmitoyl Ethyltrimonium Methosulfate...
Formula
C22H47NO6S
Mol. Weight
453.70
CAS #
-
Form
Powder
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Surfactant Emulsifying
Anti-Aging
Moisturizing
Improves Elasticity
Mixes oil and water
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
3
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2012
Regulatory Status
USA✔ permitted
CANADA✔ permitted
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR