Palmitoyl Ethyltrimonium Methosulfate

AKA: Surfactive V 16, 116246-03-8, Palmitoyl ethyltrimonium methosulfate [INCI], Ethanaminium, Methyl sulfate, Methyl sulfate (1:1)
Synthetic
Cleanser
Emulsifier
Plant Oil
Not Clean
The CIR Expert Panel concluded the following ingredients are safe in the present practices of use and concentration described in the safety assessment when formulated to be non-irritating...Palmitoyl Ethyltrimonium Methosulfate...
Formula
C22H47NO6S
Mol. Weight
453.70
CAS #
-
Form
Powder
Functions
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Surfactant Emulsifying
Anti-Aging
Moisturizing
Improves Elasticity
Mixes oil and water
Traditional Use
Developed in the late 20th century as a synthetic quaternary ammonium compound. Created to serve as a conditioning and antistatic agent in cosmetics, replacing some traditional plant-based conditioning ingredients.
EWG
3
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
CANADApermitted
Regulatory Agencies
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing
🛡️Safety-assessed1 review
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR