Palmitoyl Glycine

AKA: N-Palmitoylglycine, 2441-41-0, 2-(hexadecanoylamino)acetic acid, N-Palmitoyl glycine, N-HEXADECANOYLGLYCINE, Elmiric acid, N-(1-Oxohexadecyl)glycine, N-hexadecanoyl-glycine
Synthetic
Cleanser
Skin Conditioner
Hair Care
Amino Acid
Clean
N-hexadecanoylglycine is an N-acylglycine in which the acyl group is specified as hexadecanoyl (palmitoyl). It has a role as a marine metabolite and a human metabolite. It is a N-acylglycine 16:0 and a fatty amide. It is functionally related to a hexadecanoic acid. It is a conjugate acid of a N-hexadecanoylglycinate.
Formula
C18H35NO3
Mol. Weight
313.50
CAS #
2441-41-0
Form
Liquid
State
Solid
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Anti-Aging
Moisturizing
Improves Elasticity
Removes dirt and impurities
Softens and detangles hair
Traditional Use
A synthetic amino acid conjugate created by combining palmitic acid with glycine. Designed as a modern skincare ingredient to improve hydration and skin barrier function.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
CANADApermitted
Regulatory Agencies
Skin Types
all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing
🛡️Safety-assessed2 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR