Palmitoyl Hexapeptide-12



AKA: 171263-26-6, Palmitoyl hexapeptide-12 [INCI], N-Palmitoyl-val-gly-val-ala-pro-gly, Glycine, 2-((S)-1-((2S, 5S, 11S)-5, 11-Diisopropyl-2-methyl-4, 7, 10, 13-tetraoxo-3, 6, 9, 12-tetraazaoctacosan-1-oyl)pyrrolidine-2-carboxamido)acetic acid, 2-[[(2S)-1-[(2s)-2-[[(2s)-2-[[2-[[(2s)-2-(hexadecanoylamino)-3-methylbutanoyl]amino]acetyl]amino]-3-methylbutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]acetic acid
Plant-Derived Synthetic
Skin Conditioner
Amino Acid
Clean
Glycine, N-(1-oxohexadecyl)-L-valylglycyl-L-valyl-L-alanyl-L-prolyl-
Formula
C38H68N6O8
Mol. Weight
737.00
CAS #
171263-26-6
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Boosts collagen production
Reduces fine lines
Traditional Use
A synthetic peptide developed in the 21st century as a biomimetic ingredient designed to signal collagen production in skin. Created to replicate anti-aging benefits traditionally sought from plant extracts and proteins.
Skin Types
●all-skin-types, gentle
Best For
Wrinkles
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR