Palmitoyl Pentapeptide-4

AKA: 214047-00-4, L-Serine, Palmitoyl pentapeptide-3, Oristar popp, Lipopentapeptide 3, PAL-Lys-Thr-Thr-Lys-Ser, Palmitoyl pentapeptide-4 [INCI]
Vital Skincare Concealer - Atelier D1
Westman Atelier
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Vital Skincare Concealer - Atelier D2
Westman Atelier
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Vital Skincare Concealer - Atelier D3
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Vital Skincare Concealer - Atelier D4
Westman Atelier
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Vital Skincare Concealer - Atelier L1
Westman Atelier
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Vital Skincare Concealer - Atelier L2
Westman Atelier
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Vital Skincare Concealer - Atelier L3
Westman Atelier
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Vital Skincare Concealer
Westman Atelier
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Vital Skincare Concealer - Atelier M1
Westman Atelier
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Vital Skincare Concealer - Atelier M2
Westman Atelier
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Vital Skincare Concealer - Atelier M3
Westman Atelier
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Vital Skincare Concealer - Atelier M4
Westman Atelier
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Vital Skincare Concealer - Atelier T1
Westman Atelier
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Vital Skincare Concealer - Atelier T2
Westman Atelier
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Vital Skincare Concealer - Atelier T3
Westman Atelier
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Vital Skincare Concealer - Atelier T4
Westman Atelier
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Synthetic
Skin Conditioner
Clean
OriginSynthesized from amino acid building blocks belonging to the peptide compound family. Produced through peptide bond formation via solid-phase peptide synthesis or liquid-phase coupling methods.
Lysine, synthetic pentapeptide with serine, and threonine, hexadecanoyl derivatives
Formula
C39H75N7O10
Mol. Weight
802.10
CAS #
-
Form
Powder
Skin Types
●all-skin-types
Best For
Wrinkles
Pregnancy & Breastfeeding Safe
Yes
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Boosts collagen production
Reduces fine lines
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not Phototoxic
Lab (in vitro) test found no phototoxicity in the CIR safety assessment (CIR 887)
Not a Sensitizer
5 studies / 5 not sensitizing (CIR 887)
Mixed Skin Irritation Results
7 studies / 1 mixed / 6 not irritating / reactions slight (CIR 887)
Mixed Eye Irritation Results
4 studies / 2 irritating / 2 not irritating / reactions slight to moderate (CIR 887)
Concentration Guide
Leave-on0.00036–0.0012%
Rinse-off0.000005–0.0035%
0%50%100%
CIR reported use · report published 2024
Regulatory Status
USA✔ permitted
CANADA✔ permitted
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR