murphyPalmitoyl Proline
AKA: 59441-32-6, 1-(1-Oxohexadecyl)-L-proline, L-Proline, SEPIFEEL ONE, N-PALMITOYL-L-PROLINE, PALMITOYL PROLINE [INCI]
Synthetic
Skin Conditioner
Hair Care
Amino Acid
Clean
OriginDerived from the amino acid proline and palmitic acid, both synthesized through petrochemical processes. Synthesized through esterification, chemically bonding palmitic acid to proline via condensation reaction.
The panel concluded that the 115 amino acid alkyl amides listed below are safe in the present practices of use and concentration in cosmetics, when formulated to be non-irritating...Palmitoyl Proline...
Formula
C21H39NO3
Mol. Weight
353.50
CAS #
59441-32-6
Form
Powder
Skin Types
●all-skin-types
Best For
Loss of Elasticity
Pregnancy & Breastfeeding Safe
Yes
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR