Palmitoyl Silk Amino Acids

AKA: Silk Amino Acid Derivative

Synthetic

Cleanser

Skin Conditioner

Hair Care

Amino Acid

Acid

Not Clean

Amino acids, silk, reaction products with hexadecanoyl chloride

Effective at 0.33%

CAS #

227200-39-7

Form

Powder

Functions

Cleansing

Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.

Hair Conditioning

A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.

Anti-Aging

Moisturizing

Improves Elasticity

Removes dirt and impurities

Softens and detangles hair

Traditional Use

A modern conditioning ingredient combining palmitic acid with amino acids derived from silk protein. Developed to enhance the luxurious feel and smoothing properties of silk in cosmetic formulations.

EWG

CIR

Safe as used

Pregnancy

Yes

CIR Safety Findings

Not a Sensitizer

medical-approval

all-shades-safe

Concentration Guide

0.0017%

0.65%

0%1%

Reported use

CIR reported use: 0.0017-0.65

Regulatory Status

USA✔ permitted

CANADA✔ permitted

Regulatory Agencies

EWG CIR FDA Health Canada

Skin Types

●all-skin-types

Best For

Loss of Elasticity

Pregnancy & Breastfeeding Safe

Yes

The paper trail

🔬Peer-reviewednone on file

⚖️Regulatory1 listing →

🛡️Safety-assessed1 review →

Counts, not a verdict. A listing isn't a study. The trail, you decide.

Verified Jun 2026

Data: CosIng · EWG · CIR