Palmitoyl Tetrapeptide-7
molecular structure · PubChem
AKA: 221227-05-0, N-Palmitoylrigin, Palmitoyl-GQPR, L-Arginine, (2S)-2-(((2S)-1-((2S)-4-carbamoyl-2-(2-hexadecanamidoacetamido)butanoyl)pyrrolidin-2-yl)formamido)-5-((diaminomethylidene)amino)pentanoic acid, (2S)-2-{[(2S)-1-[(2S)-4-carbamoyl-2-(2-hexadecanamidoacetamido)butanoyl]pyrrolidin-2-yl]formamido}-5-[(diaminomethylidene)amino]pentanoic acid
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The Body Essentials Mini
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The Hand Duo
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The Hand-Lip Moisture Duo
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Synthetic
Skin Conditioner
Clean
OriginDerived from amino acids and synthesized through peptide bond formation via solid-phase peptide synthesis. Constructed by sequentially coupling four amino acids (palmitoyl group attached to tetrapeptide chain) using chemical condensation.
Palmitoyl Tetrapeptide-7 is the reaction product of palmitic acid and Tetrapeptide-7
Formula
C34H62N8O7
Mol. Weight
694.90
CAS #
-
Form
Powder
Skin Types
●all-skin-types
Best For
Wrinkles
Pregnancy & Breastfeeding Safe
Yes
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Boosts collagen production
Reduces fine lines
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Skin Irritant
1 study / 1 not irritating (CIR 633)
Not a Sensitizer
1 study / 1 not sensitizing (CIR 633)
Eye Irritant in Testing
1 study / 1 irritating / reactions slight (CIR 633)
Concentration Guide
Leave-on0.00001–0.0015%
Rinse-off0.000005–0.0007%
0%50%100%
CIR reported use · 2014 survey
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR
murphy