Palmitoyl Tripeptide 1

Palmitoyl Tripeptide 1 1
photograph
AKA: 147732-56-7, Palmitoyl Tripeptide-1, Palmitoyl oligopeptide, L-Lysine, Pal-val-gly-val-ala-pro-gly-oh, (2S)-6-amino-2-[(2S)-2-(2-hexadecanamidoacetamido)-3-(1H-imidazol-4-yl)propanamido]hexanoic acid, (2S)-6-amino-2-((2S)-2-(2-hexadecanamidoacetamido)-3-(1H-imidazol-4-yl)propanamido)hexanoic acid, BIOPEPTIDE CL
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Synthetic
Skin Conditioner
Synthetic
Clean
OriginSynthesized from palmitic acid and tripeptide amino acid chains through peptide bond formation and esterification. Produced via solid-phase peptide synthesis or liquid-phase coupling of the palmitoyl moiety to the tripeptide sequence.
See other relationships...
Formula
C30H54N6O5
Mol. Weight
578.80
CAS #
147732-56-7
Form
Powder
Skin Types
●all-skin-types
Best For
General
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Conditions Skin
Softens & Smooths
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory0 listings
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Insufficient
Pregnancy
—
CIR Safety Findings
Not a Sensitizer
2 studies / 2 not sensitizing (CIR 633)
Eye Irritant in Testing
2 studies / 2 irritating / reactions slight (CIR 633)
Mixed Skin Irritation Results
4 studies / 2 mixed / 2 not irritating / reactions slight to moderate (CIR 633)
Concentration Guide
Leave-on0.0000001–0.001%
Rinse-off0.0001–0.0008%
0%50%100%
CIR reported use · 2014 survey
Regulatory Status
USAunder review
CANADA✔ permitted
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR