Panthenyl Ethyl Ether Acetate

AKA: Panthenyl ethyl ether acetate [INCI], 119516-54-0, Butanamide
Synthetic
Skin Conditioner
Hair Care
B Vitamin
Not Clean
Butanamide, 2-hydroxy-4-acetyloxy-3,3-dimethyl-N-(3-ethoxypropyl)-
Formula
C13H25NO5
Mol. Weight
275.34
CAS #
667-83-4
Form
Liquid
Functions
Antistatic
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Reduces Static
Conditions Hair
Antioxidant Protection
Reduces Inflammation
Wound Healing
Reduces flyaways
Softens and detangles hair
Traditional Use
Developed in the mid-20th century as a synthetic derivative of panthenol (vitamin B5). Created to provide improved stability and skin penetration compared to panthenol, while maintaining moisturizing and conditioning benefits in cosmetics.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
medical-approval
all-shades-safe
Mild Irritant
Regulatory Status
USApermitted
CANADApermitted
Regulatory Agencies
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper
⚖️Regulatory1 listing
🛡️Safety-assessed1 review
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR