Panthenyl Ethyl Ether Acetate

AKA: Panthenyl ethyl ether acetate [INCI], 119516-54-0, Butanamide
Synthetic
Skin Conditioner
Hair Care
Not Clean
OriginDerived from panthenol and ethanol, belonging to the synthetic alcohol ether ester chemical family. Synthesized through esterification of panthenol derivatives with acetic anhydride and ethyl alcohol.
Butanamide, 2-hydroxy-4-acetyloxy-3,3-dimethyl-N-(3-ethoxypropyl)-
Formula
C13H25NO5
Mol. Weight
275.34
CAS #
667-83-4
Form
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Antistatic
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Reduces Static
Conditions Hair
Antioxidant Protection
Reduces Inflammation
Wound Healing
Reduces flyaways
Softens and detangles hair
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer (CIR Panel on the ingredient group)
CIR Panel statement covering this group of ingredients / not tested individually (CIR 737)
Not a Skin Irritant (CIR Panel on the ingredient group)
CIR Panel statement covering this group of ingredients / not tested individually (CIR 737)
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2022
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR
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