Pantothenic Acid

AKA: D-pantothenic acid, 79-83-4, Vitamin B5, Chick antidermatitis factor, (+)-Pantothenic acid, Vitamin B-5, Kyselina pantothenova, D(+)-N-(2, 4-Dihydroxy-3, 3-dimethylbutyryl)-beta-alanine, Pantothenic acid (d)
Synthetic
Skin Conditioner
Hair Care
Acid
Clean
OriginPantothenic acid is synthesized from starting materials including formaldehyde, acetylene, and β-alanine through multi-step organic synthesis. The compound is produced via condensation reactions combining these precursors under controlled chemical conditions.
Propanoic acid, 3-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)amino-, (R)-
Solubility Soluble
Formula
C9H17NO5
Mol. Weight
219.23
CAS #
79-83-4
Form
Liquid
State
Viscous liquid; Unstable and extremely hygroscopic; [Merck Index]
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Antistatic
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer (CIR Panel on the ingredient group)
CIR Panel statement covering this group of ingredients / not tested individually (CIR 737)
Not a Skin Irritant (CIR Panel on the ingredient group)
CIR Panel statement covering this group of ingredients / not tested individually (CIR 737)
Concentration Guide
Leave-on0.0001–0.0034%
Rinse-off0.001%
0%50%100%
CIR reported use · 2016 survey
Regulatory Status
USA✔ permitted
CANADA✔ permitted
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR