papain

AKA: Papaya protease, Caricain
Synthetic
Skin Conditioner
Hair Care
Enzyme
Clean
OriginPapain is derived from the papaya plant (Carica papaya) native to Central and South America. It is produced through recombinant DNA technology using fermentation in microorganisms to synthesize the enzyme.
Papain
CAS #
9001-73-4
Form
Powder
Skin Types
●all-skin-types, gentle
Best For
Uneven Texture
Pregnancy & Breastfeeding Safe
Caution
Functions
Antistatic
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
2
CIR
Insufficient
Pregnancy
Caution
Regulatory Status
USAunder review
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: CosIng · EWG · CIR