PEG-16
AKA: Polyethylene Glycol 16, Macrogol 16
Synthetic
Humectant
Solvent
Clean
Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, (16 mol EO average molar ratio)
CAS #
25322-68-3
Form
Liquid
Functions
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Locks In Moisture
Traditional Use
A short-chain polyethylene glycol polymer developed in the mid-20th century. Used as a humectant and solubilizer in cosmetics to improve hydration and ingredient compatibility.
EWG
2
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Agencies
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: CosIng · EWG · CIR