PEG-45

AKA: Polyethylene glycol 45, Macrogol 45, PEG 45
Synthetic
Humectant
Solvent
Clean
OriginProduced from ethylene oxide, a petrochemical derivative synthesized through catalytic oxidation of ethylene. Created by sequential polymerization of ethylene oxide monomers under controlled temperature and pressure conditions.
Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy- (45 mol EO average molar ratio)
CAS #
25322-68-3
Form
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Binding
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Locks In Moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
2
CIR
Safe as used
Pregnancy
Yes
Regulatory Status
USA✔ permitted
CANADA✔ permitted
Regulatory Agencies
Verified Jun 2026
Data: CosIng · EWG · CIR