PEG-45M

AKA: Polyethylene glycol 45M, Macrogol 45M, PEG 45M

Synthetic

Humectant

Clean

Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy- (45,000 mol EO average molar ratio)

CAS #

25322-68-3

Form

Liquid

Functions

Humectant

A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.

Locks In Moisture

Traditional Use

A very high-molecular-weight polyethylene glycol developed for industrial and cosmetic applications. Used as a thickener and texture modifier in modern skincare and cosmetic formulations.

EWG

CIR

Safe as used

Pregnancy

Yes

Restricted By

Credo Beauty Whole Foods Premium Body Care Beauty Heroes MADE SAFE EWG VERIFIED

CIR Safety Findings

Not a Sensitizer

medical-approval

all-shades-safe

Regulatory Status

USA✔ permitted

CANADA✔ permitted

Regulatory Agencies

EWG CIR FDA Health Canada

Skin Types

●all-skin-types

Best For

General

Pregnancy & Breastfeeding Safe

Yes

The paper trail

🔬Peer-reviewednone on file

⚖️Regulatory1 listing →

🛡️Safety-assessed1 review →

Counts, not a verdict. A listing isn't a study. The trail, you decide.

Verified Jun 2026

Data: CosIng · EWG · CIR