murphyPEG-75
molecular structure · PubChem
AKA: Polyethylene Glycol 75, PEG 75, Macrogol 75
Synthetic
Humectant
Solvent
Clean
OriginDerived from ethylene oxide, a petrochemical compound produced through catalytic oxidation of ethylene. Synthesized through polymerization of ethylene oxide monomers to create a polymer chain of approximately 75 units.
Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy- (75 mol EO average molar ratio)
CAS #
25322-68-3
Form
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Binding
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Locks In Moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
2
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Mixed Eye Irritation Results
2 studies / 1 irritating / 1 not irritating (CIR 88)
Mixed Skin Irritation Results
7 studies / 2 irritating / 5 not irritating / reactions mild (CIR 88 and 548)
Mixed Sensitization Results
5 studies / 2 sensitizing / 3 not sensitizing / plus 3 case reports (CIR 88 and 548)
Regulatory Agencies
Verified Jun 2026
Data: CosIng · EWG · CIR