murphyPEG-80 Sorbitan Palmitate
molecular structure · PubChem
AKA: Polysorbate 40, Tween 40
Synthetic
Cleanser
Emulsifier
Not Clean
OriginTypically derived from sorbitol (a sugar alcohol) and palmitic acid, often from palm oil or coconut oil. Synthesized through esterification of sorbitol with palmitic acid, then polyethylene glycol chains are added via ethoxylation.
Sorbitan, monohexadecanoate, poly(oxy-1,2-ethanediyl) derivs. (80 mol EO average molar ratio)
CAS #
9005-66-7
Form
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Cleansing Surfactant
Emulsifier
Removes Impurities
Mixes Oil & Water
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Skin Irritant
1 study / 1 not irritating (CIR 296)
Eye Irritant in Testing
1 study / 1 irritating / reactions minimal (CIR 296)
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2015
Regulatory Agencies
Verified Jun 2026
Data: CosIng · EWG · CIR