Pentaerythrityl Tetraisostearate

AKA: 62125-22-8, Pentaerythritol tetraisostearate, CRODAMOL PTIS, PELEMOL PTIS, DUB PTIS, KAK PTI
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Plant-Derived
Emollient
Cleanser
Emulsifier
Skin Conditioner
Clean
OriginDerived from isostearic acid, a saturated branched-chain fatty acid typically sourced from hydrogenated vegetable oils. Synthesized through esterification of pentaerythritol with isostearic acid under controlled conditions.
2,2-bis[[(1-Oxoisooctadecyl)oxy]methyl]-1,3-propanediyl bis(isooctadecanoate)
Formula
C77H148O8
Mol. Weight
1202.00
CAS #
62125-22-8
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Locks In Moisture
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Skin Irritant
1 study / 1 not irritating (CIR 585)
Not a Sensitizer
1 study / 1 not sensitizing (CIR 585)
Concentration Guide
Leave-on0.1–55%
Rinse-off0.1–0.8%
0%50%100%
CIR reported use · report published 2015
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR