murphyPentasodium Triphosphate
AKA: 7758-29-4, Armofos, Thermphos, Rhodiaphos LV, Thermphos N, Triphosphoric acid, Pentasodium salt, Thermphos SPR, Thermphos L 50
Synthetic
Chelating Agent
Not Clean
OriginProduced from phosphoric acid and sodium compounds through chemical synthesis. Created by reacting sodium hydroxide with phosphoric acid under controlled conditions.
The CIR Expert Panel concluded that the following 31 ingredients are safe in the present practices of use and concentration in cosmetics as described in this safety assessment, when formulated to be non-irritating...Pentasodium Triphosphate...
Solubility Freely soluble in water. Insoluble in ethanol
Formula
Na5O10P3
Mol. Weight
367.86
CAS #
7758-29-4
Form
Powder
State
Dry Powder, Liquid; Pellets or Large Crystals; NKRA; Other Solid; Dry Powder
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Buffering
Chelating
Grabs onto metal ions in water that would destabilize the formula. Keeps your product from going bad or changing color.
Fights Acne
Maintains optimal pH
Binds metal ions
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Mixed Skin Irritation Results
5 studies / 4 irritating / 1 not irritating / reactions slight to moderate (CIR 710)
Mixed Eye Irritation Results
2 studies / 1 irritating / 1 mixed / reactions mild (CIR 710)
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2021
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR