Pentylene Glycol

Pentylene Glycol 1
molecular structure · PubChem CID 93000
AKA: 1, 2-Pentanediol, 5343-92-0, 2-Dihydroxypentane
3 Piece Classic Suncare Travel Set
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advanced retinol gel 0.5%
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the anti aging day and night ritual
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beginner retinol gel 0.1%
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Synthetic
Solvent
Skin Conditioner
Clean
OriginDerived from petroleum-based hydrocarbons or synthesized from propylene glycol as a starting material. Produced through catalytic hydrogenation and polymerization reactions to create the five-carbon glycol chain.
structure in first source
Formula
C5H12O2
Mol. Weight
104.15
CAS #
5343-92-0
Form
Liquid
State
Liquid
Skin Types
●all-skin-types, gentle
Best For
Dehydration
Pregnancy & Breastfeeding Safe
Yes
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Locks in moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
2
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not Phototoxic (CIR Panel on the ingredient group)
CIR Panel statement covering this group of ingredients; not tested individually (CIR 576)
Not a Skin Irritant
1 study / 1 not irritating (CIR 576)
Not a Sensitizer
1 study / 1 not sensitizing / plus 1 case report (CIR 576)
Eye Irritant in Testing
1 study / 1 irritating / reactions slight (CIR 576)
Concentration Guide
Leave-on0.005–5%
Rinse-off0.001–5%
0%50%100%
CIR reported use · 2010 survey
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR