Pentylene Glycol
molecular structure · PubChem
AKA: 1, 2-Pentanediol, 5343-92-0, 2-Dihydroxypentane
Synthetic
Solvent
Skin Conditioner
Clean
structure in first source
Effective at 2.5%
Formula
C5H12O2
Mol. Weight
104.15
CAS #
5343-92-0
Form
Liquid
State
Liquid
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Locks in moisture
Traditional Use
A synthetic humectant and preservative booster developed in the late 20th century. Created to improve hydration and product stability in modern skincare formulations.
EWG
2
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
ewg-2
medical-approval
pregnancy-nursing-safe
all-shades-safe
Potential Sensitizer
Concentration Guide
0.005%
5.0%
0%7%
Reported use
CIR reported use: 0.3-5 | 0.005-4
Regulatory Agencies
Skin Types
●all-skin-types, gentle
Best For
Dehydration
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
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Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR