Phosphatidylglycerol

AKA: CHEBI:17517, PtdGro, Phosphatidylglycerols, Glycerol Phosphoglycerides, Phosphoglycerides, 3(3-phosphatidyl-)glycerol, 3-(3-sn-phosphatidyl)glycerol, Epitope ID:135398
Synthetic
Emulsifier
Skin Conditioner
Clean
OriginDerived from plant oils such as soybean, rapeseed, or sunflower through glycerolysis of phospholipids. Synthesized by esterifying glycerol with fatty acids and phosphoric acid derivatives.
Phosphatidylglycerol is the phospholipid that conforms to the formula:(structure)where RCO- represents naturally occurring fatty acids
Formula
C8H23O7P
Mol. Weight
262.24
CAS #
92347-24-5
Form
Liquid
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Stabilizes Emulsion
Skin Conditioning Miscellaneous
Skin Protecting
Emulsifier
Antioxidant Protection
Reduces Inflammation
Locks In Moisture
Improves skin feel
Shields skin from damage
Keeps product blended
Mixes oil and water
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
0%50%100%
Reg. limit 45%
CIR lists it as not reported to be in use.
CIR · report published 2020
FDA OTC limit: 45% (Skin Protectant). Also listed as anorectal protectant at 10-45% in 21 CFR 346.14 Source: FDA OTC Monograph, 21 CFR 347.10.
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR