Phosphatidylinositol

AKA: Inositol phospholipid
Synthetic
Antioxidant
Cleanser
Emulsifier
Skin Conditioner
Not Clean
OriginPhosphatidylinositol is a phospholipid synthesized from glycerol, fatty acids, inositol, and phosphoric acid precursors. It is produced through esterification and phosphorylation reactions combining these components into the final lipid structure.
Phosphatidylinositol is a cosmetic ingredient used as antioxidant, skin conditioning, surfactant - emulsifying. Assessed as safe by the CIR.
CAS #
-
Form
Powder
Skin Types
●all-skin-types
Best For
Dehydration
Pregnancy & Breastfeeding Safe
Yes
Functions
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Locks in moisture
Neutralizes free radicals
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2020
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: CosIng · EWG · CIR