Phosphatidylserine

AKA: Phosphotidylserine, Distearoylphosphatidylserine, 1446756-47-3, (2S)-2-amino-3-[[(2R)-2, 3-di(octadecanoyloxy)propoxy]-hydroxyphosphoryl]oxypropanoic acid, Phosphatidyl Serines, Serines, Serine Phosphoglycerides
Synthetic
Emulsifier
Skin Conditioner
Barrier Support
Hair Care
Clean
OriginDerived from soybean, sunflower, or other plant oils as the starting material. Synthesized through esterification of glycerol with fatty acids and phosphoric acid derivatives.
Fatty acid diglycerides, phosphate monoesters, 2-amino-2-carboxyethyl ester
Formula
C42H82NO10P
Mol. Weight
792.10
CAS #
1446756-47-3
Form
Powder
State
Solid
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Emulsion Stabilising
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Protecting
Helps rebuild and strengthen your skin barrier — the invisible shield that keeps moisture in and irritants out. Essential after over-exfoliating or harsh weather.
Nourishes & Protects
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2020
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR