murphyPhytonadione
AKA: VITAMIN K1, 84-80-0, Phylloquinone, Phytomenadione, Phytylmenadione, Mephyton, 3-Phytylmenadione, Monodion, Synthex P
Synthetic
Skin Conditioner
Synthetic
Not Clean
OriginPhytonadione is synthesized from 2-methyl-1,4-naphthoquinone (menadione) as the primary chemical precursor. The synthesis involves alkylation of menadione with a phytyl side chain through catalytic hydrogenation and condensation reactions.
Vitamin K1, also called phylloquinone or phytonadione, is a fat soluble vitamin. Phylloquinone is a cofactor of the enzyme γ-carboxylase, which modifies and activates precursors to coagulation factors II, VII, IX, and X. It is indicated in the treatment of coagulation disorders due to faulty formation of coagulation factors II, VII, IX, and X caused by deficiency or interference in the activity of vitamin K. Phylloquinone has been synthesized since at least 1939, and was approved by the FDA prior to 1955.
Solubility Insoluble in water
Formula
C31H46O2
Mol. Weight
450.70
CAS #
84-80-0, 81818-54-4
Form
Oil
State
Yellow viscous liquid; [Merck Index] Dark yellow or green viscous liquid; [Sigma-Aldrich MSDS]
Skin Types
●all-skin-types
Best For
Dark Circles
Pregnancy & Breastfeeding Safe
Yes
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning Miscellaneous
Improves skin feel
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory0 listings
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR