Poloxamer 101

AKA: Pluronic 101, Poloxapropylene, Poloxathylene
Synthetic
Cleanser
Emulsifier
Clean
OriginPoloxamer 101 belongs to the noniionic surfactant family, synthesized from propylene oxide and ethylene oxide polymers. Produced through sequential polymerization of ethylene oxide onto a polypropylene glycol backbone.
Oxirane, methyl-, polymer with oxirane (2;16)
CAS #
9003-11-6
Form
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Surfactant Cleansing
Surfactant Emulsifying
Anti-Inflammatory
Antimicrobial
Strengthens Barrier
Lifts away dirt and oil
Mixes oil and water
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
2
CIR
Safe as used
Pregnancy
Yes
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: CosIng · EWG · CIR