Poloxamer 108

AKA: 106392-12-5, 2-methyloxirane;oxirane, TERGITOL(TM)XH(NONIONIC), Pluronic F-68, Pluronic L, 691397-13-4, Pluronic L 122

Synthetic

Cleanser

Emulsifier

Not Clean

Oxirane, methyl-, polymer with oxirane (46;16)

Formula

C5H10O2

Mol. Weight

102.13

CAS #

9003-11-6

Form

Liquid

Functions

Cleansing

Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.

Emulsifying

Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.

Cleansing Surfactant

Emulsifier

Fights Bacteria

Reduces Inflammation

Locks In Moisture

Removes Impurities

Mixes Oil & Water

Traditional Use

Synthesized in the 1950s as part of the poloxamer polymer family. Functions as a surfactant and thickening agent in creams, lotions, and cleansing products.

EWG

CIR

Safe as used

Pregnancy

Yes

CIR Safety Findings

Not an Irritant

medical-approval

all-shades-safe

Regulatory Status

USA✔ permitted

EU⚠ restricted

JAPAN⚠ restricted

CANADA⚠ restricted

Regulatory Agencies

EWG CIR FDA EU COSING Health Canada

Skin Types

●all-skin-types

Best For

General

Pregnancy & Breastfeeding Safe

Yes

The paper trail

🔬Peer-reviewednone on file

⚖️Regulatory1 listing →

🛡️Safety-assessed2 reviews →

Counts, not a verdict. A listing isn't a study. The trail, you decide.

Verified Jun 2026

Data: PubChem · CosIng · EWG · CIR