Poloxamer 122
molecular structure · PubChem
AKA: Pluronic 122
Synthetic
Cleanser
Emulsifier
Not Clean
Oxirane, methyl-, polymer with oxirane (5:21)
CAS #
9003-11-6
Form
Liquid
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Surfactant Cleansing
Surfactant Emulsifying
Anti-Inflammatory
Antimicrobial
Strengthens Barrier
Lifts away dirt and oil
Mixes oil and water
Traditional Use
A poloxamer variant created for cosmetic use in the latter half of the 20th century. Used as an emulsifier and viscosity modifier in skincare and personal care products.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: CosIng · EWG · CIR