Poloxamer 122
molecular structure · PubChem
AKA: Pluronic 122
Synthetic
Cleanser
Emulsifier
Not Clean
OriginPoloxamer 122 belongs to the poloxamer family, synthetic block copolymers derived from propylene oxide and ethylene oxide. Synthesized through sequential polymerization of propylene oxide followed by ethylene oxide addition onto a polypropylene glycol backbone.
Oxirane, methyl-, polymer with oxirane (5:21)
CAS #
9003-11-6
Form
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Surfactant Cleansing
Surfactant Emulsifying
Anti-Inflammatory
Antimicrobial
Strengthens Barrier
Lifts away dirt and oil
Mixes oil and water
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: CosIng · EWG · CIR
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