Poloxamer 123
molecular structure · PubChem
AKA: Pluronic 123
Synthetic
Cleanser
Emulsifier
Not Clean
OriginSynthesized from ethylene oxide and propylene oxide polymers derived from petroleum-based starting materials. Produced through sequential polymerization and block copolymerization reactions to create the final surfactant structure.
Oxirane, methyl-, polymer with oxirane (7;21)
CAS #
9003-11-6
Form
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Surfactant Cleansing
Surfactant Emulsifying
Anti-Inflammatory
Antimicrobial
Strengthens Barrier
Lifts away dirt and oil
Mixes oil and water
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: CosIng · EWG · CIR
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