murphyPoloxamer 181
molecular structure · PubChem
AKA: Pluronic 181
Synthetic
Cleanser
Emulsifier
Not Clean
OriginPoloxamer 181 is synthesized from propylene oxide and ethylene oxide polymers derived from petroleum. It is produced through sequential polymerization of these oxides onto a polypropylene glycol backbone.
Oxirane, methyl-, polymer with oxirane (3;30)
CAS #
9003-11-6
Form
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Surfactant Cleansing
Surfactant Emulsifying
Anti-Inflammatory
Antimicrobial
Strengthens Barrier
Lifts away dirt and oil
Mixes oil and water
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: CosIng · EWG · CIR