Poloxamer 335

AKA: Pluronic 335, Polyoxypropylene Polyoxyethylene Block Copolymer

Synthetic

Cleanser

Emulsifier

Clean

Oxirane, methyl-, polymer with oxirane (38;54)

CAS #

9003-11-6

Form

Liquid

Functions

Cleansing

Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.

Emulsifying

Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.

Surfactant Cleansing

Surfactant Emulsifying

Anti-Inflammatory

Antimicrobial

Strengthens Barrier

Lifts away dirt and oil

Mixes oil and water

Traditional Use

Developed as a synthetic nonionic surfactant in the mid-20th century for cosmetic applications. Used as an emulsifier and solubilizing agent in modern skincare formulations with no pre-modern history.

EWG

CIR

Safe as used

Pregnancy

Yes

CIR Safety Findings

Not an Irritant

medical-approval

all-shades-safe

Regulatory Status

USA✔ permitted

EU⚠ restricted

JAPAN⚠ restricted

CANADA⚠ restricted

Regulatory Agencies

EWG CIR FDA EU COSING Health Canada

Skin Types

●all-skin-types

Best For

General

Pregnancy & Breastfeeding Safe

Yes

The paper trail

🔬Peer-reviewednone on file

⚖️Regulatory1 listing →

🛡️Safety-assessed3 reviews →

Counts, not a verdict. A listing isn't a study. The trail, you decide.

Verified Jun 2026

Data: CosIng · EWG · CIR