Poloxamer 338
molecular structure · PubChem
AKA: Pluronic 338, Polyoxypropylene Polyoxyethylene Block Copolymer
Synthetic
Cleanser
Emulsifier
Clean
Oxirane, methyl-, polymer with oxirane (128;54)
CAS #
9003-11-6
Form
Liquid
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Cleansing Surfactant
Emulsifier
Fights Bacteria
Reduces Inflammation
Locks In Moisture
Removes Impurities
Mixes Oil & Water
Traditional Use
A synthetic block copolymer surfactant developed in the 1950s for cosmetic and pharmaceutical use. Employed as an emulsifier and texture enhancer in skincare products without traditional historical use.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: CosIng · EWG · CIR