Poloxamer 338
molecular structure · PubChem
AKA: Pluronic 338, Polyoxypropylene Polyoxyethylene Block Copolymer
Synthetic
Cleanser
Emulsifier
Clean
OriginProduced from ethylene oxide and propylene oxide polymers through sequential polymerization reactions. Synthesized via block copolymerization to create a nonionic surfactant with hydrophilic and hydrophobic segments.
Oxirane, methyl-, polymer with oxirane (128;54)
CAS #
9003-11-6
Form
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Cleansing Surfactant
Emulsifier
Fights Bacteria
Reduces Inflammation
Locks In Moisture
Removes Impurities
Mixes Oil & Water
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: CosIng · EWG · CIR
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