Poloxamer 403
molecular structure · PubChem
AKA: Pluronic 403, Polyoxypropylene Polyoxyethylene Block Copolymer
Synthetic
Cleanser
Emulsifier
Not Clean
OriginDerived from ethylene oxide and propylene oxide, belonging to the nonionic surfactant chemical family. Synthesized through sequential polymerization of these oxide monomers to create a block copolymer structure.
Oxirane, methyl-, polymer with oxirane (21;67)
CAS #
9003-11-6
Form
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Surfactant Cleansing
Surfactant Emulsifying
Anti-Inflammatory
Antimicrobial
Strengthens Barrier
Lifts away dirt and oil
Mixes oil and water
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: CosIng · EWG · CIR
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