Poloxamer 407
molecular structure · PubChem
AKA: Pluronic F-127, Polyoxypropylene Polyoxyethylene Block Copolymer
Synthetic
Cleanser
Emulsifier
Clean
OriginDerived from propylene oxide and ethylene oxide, members of the synthetic polymer chemical family. Synthesized through sequential polymerization of ethylene oxide onto a polypropylene glycol backbone.
Oxirane, methyl-, polymer with oxirane (98;67)
CAS #
9003-11-6
Form
Powder
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Cleansing Surfactant
Emulsifier
Antioxidant Protection
Reduces Inflammation
Locks In Moisture
Removes Impurities
Mixes Oil & Water
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: CosIng · EWG · CIR
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