Poloxamer 407
molecular structure · PubChem
AKA: Pluronic F-127, Polyoxypropylene Polyoxyethylene Block Copolymer
Synthetic
Cleanser
Emulsifier
Clean
Oxirane, methyl-, polymer with oxirane (98;67)
CAS #
9003-11-6
Form
Powder
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Cleansing Surfactant
Emulsifier
Antioxidant Protection
Reduces Inflammation
Locks In Moisture
Removes Impurities
Mixes Oil & Water
Traditional Use
Developed in the 1950s as a synthetic poloxamer surfactant widely used in cosmetics and pharmaceuticals. Functions as an emulsifier, solubilizer, and thickening agent with no traditional or historical use prior to modern chemistry.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: CosIng · EWG · CIR