Polyglycerin-6

Polyglycerin-6 molecular structure
molecular structure · PubChem
AKA: Hexaglycerol, 36675-34-0, (2S)-3-[(2S)-3-[(2S)-3-[(2R)-3-[(2S)-3-[(2S)-2, 3-dihydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropoxy]propane-1, 2-diol, HEXAGLYCERIN, FWTZRWTUPSQZOG-UGDFAFBOSA-N, (2S, 6S, 10R, 14S, 18S, 22S)-4, 8, 12, 16, 20-Pentaoxatricosan-1, 2, 10, 14, 18, 22, 23-Octaol
Synthetic
Humectant
Plant Oil
Not Clean
See also: Polyglycerin-6 (annotation moved to).
Formula
C18H38O13
Mol. Weight
462.50
CAS #
36675-34-0
Form
Liquid
Functions
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Locks In Moisture
Traditional Use
A shorter-chain glycerin ester developed for cosmetic use in the late 20th century. Functions as a humectant and emollient in moisturizers and skincare products.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR