Polyglyceryl-10 Diisostearate

AKA: DNACJYZYGAJDBK-UHFFFAOYSA-N, NCA70503
Plant-Derived
Cleanser
Emulsifier
Clean
OriginDerived from polyglycerin and isostearic acid, typically sourced from palm or coconut oils. Synthesized through esterification of polyglycerol with isostearic acid under catalytic conditions.
1,2,3-Propanetriol, homopolymer, isooctadecanoates (1:2) (10 mol glycerol average molar ratio)
Formula
C39H80O7
Mol. Weight
661.00
CAS #
63705-03-3, 102033-55-6
Form
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Emulsifier
Mixes Oil & Water
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Skin Irritant
1 study / 1 not irritating (CIR 717)
Not an Eye Irritant
1 study / 1 not irritating (CIR 717)
Concentration Guide
Leave-on0.8–2%
Rinse-off1.6–17%
0%50%100%
CIR reported use · report published 2023
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR
murphy