Polyglyceryl-10 Nonaisostearate
molecular structure · PubChem
Plant-Derived
Skin Conditioner
Clean
OriginDerived from decaglycerol and isostearic acid, both petroleum-derived synthetic compounds. Synthesized through esterification reaction between decaglycerol and isostearic acid under catalytic conditions.
nonaester of decaglycerol and isostearic acid
Form
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not Phototoxic
Animal test found no phototoxicity in the CIR safety assessment (CIR 717)
Not a Sensitizer
1 study / 1 not sensitizing (CIR 717)
Skin Irritant in Testing
1 study / 1 irritating / reactions mild (CIR 717)
Eye Irritant in Testing
1 study / 1 irritating / reactions mild (CIR 717)
Concentration Guide
Leave-onNot reported
Rinse-off0.5%
0%50%100%
CIR reported use · report published 2023
Regulatory Agencies
Verified Jun 2026
Data: CosIng · EWG · CIR
murphy