murphyPolyglyceryl-10 Pentaisostearate
molecular structure · PubChem
Plant-Derived
Emollient
Cleanser
Emulsifier
Skin Conditioner
Clean
OriginDerived from decaglycerol (polyglycerin) and isostearic acid, both typically sourced from petroleum or plant oils.
Synthesized through esterification reaction between decaglycerol and isostearic acid under controlled heat and catalytic conditions.
Pentaester of decaglycerol and isostearic acid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Locks In Moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
1 study / 1 not sensitizing (CIR 717)
Not an Eye Irritant
1 study / 1 not irritating (CIR 717)
Mixed Skin Irritation Results
4 studies / 1 irritating / 3 not irritating (CIR 717)
Concentration Guide
Leave-on2–4.8%
Rinse-offNot reported
0%50%100%
CIR reported use · report published 2023
Regulatory Agencies
Verified Jun 2026
Data: CosIng · EWG · CIR