Polyglyceryl-2 Isopalmitate/Sebacate

Polyglyceryl-2 Isopalmitate/Sebacate molecular structure
molecular structure · PubChem
Synthetic
Cleanser
Emulsifier
Clean
Mixed ester of diglycerol, isopalmitic acid and sebacic acid
Functions
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Emulsifier
Antioxidant Protection
UV Protection
Mixes Oil & Water
Traditional Use
Developed in the late 20th century as a synthetic emulsifier combining polyglycerin with plant-derived fatty acids. Created to replace traditional emulsifiers like beeswax and lanolin in modern cosmetic formulations.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: CosIng · EWG · CIR