Polyglyceryl-2 Isostearate

AKA: Diglycerol isostearate, Diglyceryl isostearate, Isooctadecanoic acid, Ester with oxybis[propanediol], Ester with oxybis(propanediol)
Plant-Derived
Cleanser
Emulsifier
Clean
OriginDerived from coconut, palm kernel, or soybean oils as the primary natural starting materials. Synthesized through esterification of polyglycerol with isostearic acid via chemical condensation.
Ester of diglycerol and isostearic acid
CAS #
73296-86-3, 81752-33-2
Form
Liquid
Skin Types
●all-skin-types, gentle
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Emulsifier
Antioxidant Protection
UV Protection
Mixes Oil & Water
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Skin Irritant in Testing
2 studies / 2 irritating / reactions slight to mild (CIR 717)
Concentration Guide
Leave-on1.6–19.3%
Rinse-offNot reported
0%50%100%
CIR reported use · report published 2023
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: CosIng · EWG · CIR