Polyglyceryl-2 Triisostearate

AKA: Neorex pgis, Salacos 43V, Cithrol PG23IS, Risorex PGIS23, Cosmol 43SV, Cosmol 43V, 120486-24-0, Diglyceryl triisostearate
Plant-Derived
Cleanser
Emulsifier
Clean
OriginDerived from vegetable oils such as coconut, palm kernel, or soybean oils as the starting material. Synthesized through esterification of polyglycerol with isostearic acid to create the emulsifying compound.
1,2,3-Propanetriol, homopolymer, isooctadecanoates (1:3) (2 mol glycerol average molar ratio)
Formula
C60H116O8
Mol. Weight
965.60
CAS #
120486-24-0
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Emulsifier
Antioxidant Protection
UV Protection
Mixes Oil & Water
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
Leave-on0.12–40%
Rinse-off1–4%
0%50%100%
CIR reported use · report published 2023
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR