Polyglyceryl-3 Diisostearate

Polyglyceryl-3 Diisostearate 1
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Polyglyceryl-3 Diisostearate 2
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Plant-Derived
Cleanser
Emulsifier
Clean
OriginDerived from glycerin and isostearic acid, plant-derived fatty acids through esterification processes. Produced by chemically bonding multiple glycerin molecules with isostearate compounds via esterification.
1,2,3-Propanetriol, homopolymer, isodecanoates (1:2) (3 mol glycerol average molar ratio)
Family
Unknown (Not directly plant-derived)
CAS #
66082-42-6, 85666-92-8
Skin Types
●all-skin-types, gentle
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Emulsifier
Brightens Skin
Mixes Oil & Water
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Skin Irritant
1 study / 1 not irritating (CIR 717)
Not a Sensitizer
1 study / 1 not sensitizing (CIR 717)
Not an Eye Irritant
1 study / 1 not irritating (CIR 717)
Concentration Guide
Leave-on0.00000015–39%
Rinse-off0.000025–29.7%
0%50%100%
CIR reported use · report published 2023
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: CosIng · EWG · CIR