Polyglyceryl-6 Sesquicaprylate

AKA: Diglyceryl dicaprylate, Diglycerin dicaprylic acid ester

Synthetic

Emollient

Cleanser

Skin Conditioner

Not Clean

OriginDerived from polyglycerin and sesquicaprylate, both synthesized from petroleum-derived or plant-based fatty acid feedstocks. Produced through esterification of polyglycerin with sesquicaprylate fatty acids under catalytic conditions.

Polyglyceryl-6 Sesquicaprylate is a mixture of mono- and diesters of Caprylic Acid and Polyglycerin-6.

CAS #

108777-93-1, 946492-22-4, 946492-23-5

Form

Liquid

Skin Types

●all-skin-types

Best For

General

Pregnancy & Breastfeeding Safe

Yes

Functions

Skin Conditioning

A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.

Emollient

Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.

Cleansing

Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.

Locks In Moisture

The paper trail

🔬Peer-reviewednone on file

⚖️Regulatory1 listing →

🛡️Safety-assessed1 review →

Counts, not a verdict. A listing isn't a study. The trail, you decide.

EWG

CIR

Safe as used

Pregnancy

Yes

Concentration Guide

CIR lists it as not reported to be in use.

CIR · report published 2023

Regulatory Status

USA✔ permitted

EU⚠ restricted

JAPAN⚠ restricted

CANADA⚠ restricted

Regulatory Agencies

EWG CIR FDA EU COSING Health Canada

Verified Jun 2026

Data: CosIng · EWG · CIR